For which condition is Buprenorphine primarily indicated?

Buprenorphine is primarily indicated for the treatment of opioid dependence. This is due to its unique pharmacological properties as a partial agonist at the mu-opioid receptor. Unlike full agonists, buprenorphine provides analgesia and alleviates withdrawal symptoms without producing the same level of euphoria, which helps to reduce the potential for abuse in patients seeking to overcome opioid addiction.

In addition to its use in dependency treatments, buprenorphine can also be employed in pain management, but its primary role is in the context of substance use disorders. This focus makes buprenorphine particularly suited for patients in recovery who may also be dealing with chronic pain while needing to avoid traditional full opioid agonists that could lead to relapse. The other options provided do not align with the main clinical purpose of buprenorphine, underscoring its specific indication for opioid dependence management.