What condition is morphine contraindicated in?

Morphine is contraindicated in asthma because it can significantly depress respiration. Asthma is characterized by airway constriction and inflammation, leading to difficulty in breathing. The use of morphine in patients with asthma can lead to respiratory depression, which may exacerbate their underlying condition and lead to serious complications.

Patients with asthma may already have compromised respiratory function, and introducing morphine, an opioid that can inhibit respiratory drive, poses a risk of severe respiratory distress. Additionally, morphine can also stimulate histamine release, which can lead to bronchoconstriction, further complicating the management of asthma symptoms.

In contrast, while individuals with hypertension, diabetes, or heart disease may experience complications related to opioid use, those conditions do not present the same direct and immediate risk to respiratory function that asthma does. This is why morphine is specifically contraindicated in patients with asthma rather than the other listed conditions.