What is one of the GI effects caused by Loperamide (Imodium)?

Loperamide, commonly known by the brand name Imodium, is an antidiarrheal medication that works by slowing down gut motility and decreasing the frequency of bowel movements. One of the primary effects of Loperamide is its ability to induce constipation. This happens because it decreases the movement of the intestines, allowing for more water absorption from the stool, resulting in firmer stools and reduced bowel frequency.

In contrast, diarrhea is the condition that Loperamide aims to treat, so it would not be a GI effect attributed to the medication. Abdominal cramps may occur as a side effect of other gastrointestinal disturbances rather than a direct effect of Loperamide itself. Nausea is also a possible side effect of various medications but is not a primary effect associated with Loperamide’s action in the gastrointestinal tract.

Therefore, recognizing Loperamide's intended purpose in managing diarrhea highlights its effect of causing constipation, which is integral to its mechanism of action.