What is the primary route of administration for Butorphanol and Nalbuphine?

Butorphanol and Nalbuphine primarily utilize the parenteral route of administration, making this the correct answer. Parenteral administration refers to delivering medications by injection, including intramuscular, intravenous, or subcutaneous routes. This method allows for rapid onset of action, which is particularly beneficial in pain management situations where immediate relief is required.

Both Butorphanol and Nalbuphine are often utilized in clinical settings, such as during surgical procedures or in emergency situations, where fast relief from acute pain is needed. Their effectiveness and the ability to bypass the gastrointestinal tract ensure that the medications are rapidly available in the bloodstream, enhancing their efficacy.

While Butorphanol can also be administered intranasally, and oral options exist for some opioid medications, the predominant and recommended clinical use is through parenteral means due to the immediate relief and reliability provided by this route. This makes the choice of parenteral administration particularly relevant when considering the characteristics and typical applications of these two medications in managing pain.